Nicola Sturgeon could keep items her estranged husband Peter Murrell paid for using SNP money unless party sues
The former first minister is under growing pressure to hand over any items purchased with SNP funds.
Drunk, aggressive and swearing...bouncer reveals what your kids really get up to at night
George Bass is a full time security guard and had a life on the frontline protecting drunk people from themselves and others
How I went from delivery driver to London's pickpocket hunter exposing street thieves on social media
Fed up with street crime, Brazilian-born Diego Galdino swapped his delivery bike for a camera and began tracking down London's pickpockets, and reveals the moment that changed everything.
The Met Police will NOT investigate the harassment of Dame Helen Mirren by a pro-Palestine activist who called the Oscar-winning actress a 'Zionist b****'
The Oscar-winning actress, 80, was called an 'evil Zionist b****' by Corbynista Tom Carroll as she walked along the street in London with her husband, Taylor Hackford.
This is the moment I knew I had to quit the police. I was a counter-terrorism expert with 24 years of experience but it was the final straw... and it explains why Henry Nowak's horrific death was no surprise
It was in 2024 that officer Paul Birch decided he could no longer remain in the police.
Entire fleet of UK attack submarines is unfit for war and stuck in dock: Fresh humiliation for our depleted Armed Forces after Chief of Staff warns Putin is 'raising the stakes'
In a fresh humiliation for Britain's Armed Forces, all five of its Astute class submarines are currently laid up awaiting maintenance and other repair work.
Royal-approved Father's Day gifts to impress - from polo shirts and sunglasses to champagne loved by Prince William and King Charles
Finding the perfect Father's Day gift isn't always easy. This year, why not take inspiration from the Royal Family? After all, every dad deserves to be treated like a king on his special day.
The lucky pets who live at some of the world's most lavish hotels, including Toto the tortoise at the Shangri-La in Mauritius and Teddy the Shetland pony at royal favourite The Goring
Meet some of the hotels with unconventional staff members and permanent residents - and even one 'manager' with surprising credentials...
Chelmsford business sold 'lamb kebabs' to takeaways - but what was inside was very different
They have been fined £500,000 for mislabelling lamb kebabs sold in restaurants and takeaways across the UK
How to stop food poisoning ruining your summer holiday - experts reveal what not to order while abroad...and whether tap water is safe to drink
Should you order steak rare on holiday? Can you use tap water to brush your teeth? Two food safety experts reveal how to reduce the risk of a sickness bug during your precious time away.
Inside the Russian resistance looking to bring down Putin: Exclusive footage shows pro-Ukraine 'Black Spark' rebels 'carrying out bomb attacks on strategic targets'
The underground movement has emerged from the shadows under the public representation of Igor Volobuev, a former banking executive who defected to Ukraine.
'Steve Jobs In Exile' Remembers the Birth of the Web and 'Making Unix Taste Sweet'
Ars Technica shares some anecdotes from Steve Jobs in Exile, a new book released last month:
[Author Geoffrey] Cain reminds us, in stunning detail, that Jobs' "exile" era at NeXT was not only critical to his evolution as a man and an entrepreneur, but that it mattered for the rest of us, too. The technological innovations that came out of NeXT — notably, the NeXTSTEP OS — continue to live on in what we now call both macOS and iOS. As Cain puts it, "NeXTSTEP was Steve's attempt to make Unix taste sweet...."
[W]hile many tech nerds know that Tim Berners-Lee created the first World Wide Web server on a NeXT machine while working in Switzerland in 1990, few know that NeXT employees were wary of bringing the news to Jobs. Why? They feared his wrath "and that he would dismiss [the web] as 'shit.'" (In another timeline, NeXT might itself have capitalized on this world-changing innovation....)
Perhaps one of the wildest anecdotes that Cain uncovered was how one voicemail changed computer history forever. In 1996, when Apple was solidly in its mediocre Performa era — and considering buying BeOS as the basis for its new operating system — a mid-level NeXT product manager asked aloud, "Why don't we just frickin' call Apple?" (NeXT was also struggling during this period.) And so someone did. As Cain writes:
Garrett left the group of managers, walked back to his office, and took a risk. He picked up his designer phone and called the head of software at Apple. He left what he described as "one of my more inspired sales pitches" on the man's voicemail, explaining why Apple should be looking at NeXT instead of Be... In any other universe, Garrett's call might have gotten him fired. But in this timeline, it worked out. And thanks to him, Steve [Jobs] was about to enter Apple's airspace once again.
Thanks to long-time Slashdot reader destinyland for sharing the article.
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Inside South Africa's whites-only enclave where young people are flocking after deciding 'it's not so wonderful elsewhere' and it's nicer to be 'the majority'
A generation has grown up in the closed world of Orania, South Africa's whites-only Afrikaner enclave on the margins of the rainbow nation that this year celebrates its 35th anniversary.
Colchester Zoo announces new arrival as 'threatened' monkey infant born
These monkeys are often killed for bush meat and caught for the pet trade
Dramatic standoff between two gunmen sparked shooting near Ohio's Old West End Festival in Toledo that injured 12 as two victims fight for their lives and shooters remain at large
Police are hunting two suspects after a shooting erupted near the Old West End Festival in Toledo, Ohio, on Saturday.
Father of 'Hell on Wheels' Mackenzie Shirilla erupts at cops after her arrest: She's 'a dumb 18-year-old'
Mackenzie Shirilla, nicknamed 'Hell on Wheels,' was arrested on November 4, 2022, months after crashing her car into a building and killing her boyfriend and their friend.
Everything you need to know as Red Arrows set to fly over Essex next week
People in two parts of Essex could spot them overhead
US forces shoot down two Iranian one-way attack drones that threatened international maritime traffic in the Strait of Hormuz
The United States military shot down two Iranian one-way attack drones that threatened maritime traffic over the Strait of Hormuz in the latest test of a fragile ceasefire in the Middle East conflict.
Kim Kardashian's daughter North, 12, teams up with ANOTHER nepo baby for new song… and fans are not happy
MULA THA ROOT OF ALL EVIL dropped Friday and was greeted by a chorus of moans from fans, who left blistering online comments dismissing the single as 'hot trash' and' 'a bunch of noise.'
Scientists Edited Human Embryo Genes. But Questions Remain
"A DNA-editing feat involving editing the genes of early stage embryos was announced this week," reports the Wall Street Journal.
They describe the feat as "a far cry from designer babies, but nevertheless a step in that direction."
Dieter Egli, an associate professor of developmental cell biology at Columbia University and his co-authors, including Nathan Treff of Nucleus Genomics, a New York-based DNA-testing startup, say the technology could help fix disease-causing mutations in embryos. "We're not throwing the final 'OK, you will have gene-edited babies tomorrow' at the public," said Egli. "That is a process that can occur through discussion matched with scientific progress...."
Previous gene-editing efforts have often used Crispr, which can cut out parts of the DNA sequence, but the technology can also cause damage if the wrong DNA is targeted or cut out. In 2018, Chinese scientist He Jianku said he used Crispr to tweak DNA in human embryos and was imprisoned for the work. The technology Egli's group used, called base editing, allows them to target individual DNA letters in sequences more precisely with fewer adverse effects... Egli's group focused on altering two genes, one that can raise the risk of heart disease and one that is tied to blood disorders like sickle cell disease, and the research showed they were sometimes able to do so successfully, in the same embryo, without damage.
"I am generally supportive of the concept of embryo editing to prevent genetic disease," said Dr. Paula Amato, a fertility expert at Oregon Health & Science University who wasn't involved in the research... Base editing has been used in human embryos before, according to peer-reviewed studies. The technology was used to correct a disease-causing mutation and an Alzheimer's disease-risk gene variant, said Alexis Komor, associate professor of biochemistry and molecular biophysics at the University of California, San Diego, who wasn't involved in the work. "There really is not any unmet medical or clinical need for this, especially from an in vitro fertilization perspective," Komor said. "Usually what you'll hear is that they're doing it just so that you know we can prevent genetic diseases, but there are so many other better ways to do that."
Using embryo editing to create babies is illegal in the U.S. and many other countries. Scientists have long worried that it is a slippery slope and that the technology could ultimately be used to promote eugenics. Her worry is that "they're basically building a blueprint" for more ethically problematic forms of embryo editing.
"In my opinion, I think this is a huge no-no," Komor said. "There's just no ethical way to use this...."
Nucleus Genomics Chief Executive Kian Sadeghi said his company plans to fund Egli's further research, building on the new findings. His company sells a polygenic embryo-screening product, which screens prospective parents' embryos and produces risk scores for their likelihood of developing disease, as well as factors like height, IQ and eye color. The company has said the IQ predictions are limited in accuracy.
The research was published online Monday on a preprint server.
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