Fat jab breakthrough as new drug could prevent potentially dangerous muscle loss triggered by taking weight loss injections
An innovative drug could slash the risk of muscle loss for patients on weight loss, a new study has suggested.
Dua Lipa and Callum Turner's baby plans: KATIE HIND speaks to insiders after the celebrity wedding of the summer - ONLY in the Spotlight newsletter
This week, the world is still mesmerised by the photos from the most glamorous wedding of the summer, if not the whole year. But I have an exclusive update for you.
England fans who went to 1986 Mexico World Cup and 'never came home' set to be reunited at this summer's tournament
They were young men in their twenties when, down on their luck and out of work, they decided to travel to Mexico to watch their beloved England.
Mrs Hinch showcases dramatic weight loss with throwback snap as she details botched gastric band surgery
Mrs Hinch has showcased her dramatic weight loss in a throwback snap on Instagram on Sunday as she detailed her botched gastric band surgery.
Starmer set to unveil long awaited defence investment plan on Thursday
A year overdue blueprint for UK defence spending is expected to be unveiled by Sir Keir Starmer on Thursday - subject to sign off by the Treasury.
Watch the moment sobbing child killer Emma Barnett confesses 'I killed him' to police officer
The article features video that some people may find distressing and upsetting
Jeff Bezos Is Funding a Wild Hunt for the Brain's 'Core Algorithm'
Jeff Bezos is backing Flourish, a new "neuro AI" startup with $500 million in funding and a reported $2.5 billion valuation, that aims to reinvent AI by studying the brain's architecture and building systems that learn continuously while using far less power than today's large language models. The company's long-term bet is that neuroscientists and AI researchers working together can uncover the brain's "core algorithm" and eventually create brain-inspired AI that runs on a tiny fraction of current compute. Wired reports: Rob Williams knows how to pitch Jeff Bezos: You write a press release as if your product has already been built. Bezos reads it and gives a thumbs up or down. Williams went through this process a lot as an executive on Amazon's "S-team," in charge of software products such as Alexa, until his departure last fall. But the pitch he made a few weeks later -- in December 2025 -- was different. Now he was collaborating with Thomas Reardon, a neuroscientist and repeat startup founder, and approaching Bezos as a funder, not a boss. Here's what Bezos, sitting on his yacht somewhere, read while Williams anxiously watched on Zoom: "Flourish is a neuro AI company that is solving the two most difficult problems facing AI today: power efficiency and continuous learning. We are building Cortex AI, the first synthetic intelligence system designed to match the computational capacity, learning efficiency, and power budget of the human brain."
A month later, I'm lunching with Reardon and Williams in the Flatiron neighborhood in New York City. Reardon gets right to the point. AI has dug itself into a hole, he says. Though increasingly powerful, large language models are greedy consumers of computer power and data. Though the inspiration for LLMs was rooted in biology, current frontier models have little in common with the human brain. A person uses about 20 watts of energy to process information; a single chip in an AI training cluster uses more than 30 times that amount. The hyperscalers require thousands of chips and gigawatts of energy, enough to power small cities. And those models need to suck up virtually all of what humans have written. Each new model requires more, more, more. For all of that, the models don't learn. Once you train them, they're stuck. The goal, Reardon tells me, is to build "a synthetic artificial intelligence brain that runs on 50 watts or less." It should adapt to its conditions, be as nimble as a human mind, and burn a tiny fraction of an LLM's compute power and energy. The proof of concept is thriving inside our skulls. "There's something fundamentally wrong with saying, "I need to basically read every book ever written 20 times over in order to learn English,'" Reardon says. "A human baby does it with a couple hundred thousand utterances."
Reardon and Williams haven't figured out yet how to build systems that match the magic of a human brain. What they have is a belief that an expert, well-resourced team -- of AI researchers and neuroscientists working essentially side by side -- can find the answer. The neuroscientists will conduct original wet lab experiments with some of the most advanced lab equipment available, to hunt for usable intel on the brain's architecture. They plan to release the models they're currently developing as near-term products on the path to a full reinvention of AI. The fuzziness of the proposal didn't bother Jeff Bezos. After reading Williams' two-pager, he chipped in $50 million. Other funding came from Lux Capital, Google Ventures, and Catalio, among others. Bezos then almost doubled his initial stake and told Reardon he'd have given more if they'd asked. Now with a war chest of $500 million and a reported valuation of $2.5 billion, Flourish just needs to invent a new way to do AI.
Read more of this story at Slashdot.
Murder investigation launched after boy, 12, dies
A murder investigation has been launched after a 12-year-old boy died in a suspected collision with a vehicle in Pilgrims Hatch, Brentwood
Murder investigation launched after boy, 12, dies
A murder investigation has been launched after a 12-year-old boy died in a suspected collision with a vehicle in Pilgrims Hatch, Brentwood
Irish pub turns their flags upside down to become the UK's first IVORY COAST boozer for the World Cup - stocking African Guinness and Ivorian food after 'a joke went too far'
The Republic of Ireland failed to qualify for this summer's showpiece in the USA, Canada, and Mexico after losing to the Czech Republic in the play-offs on penalties in March.
Brian Cox and wife Nicole pose with rarely-seen actor sons Orson, 24, and Torin, 21, as they toast their 25th wedding anniversary and his 80th birthday at a star-studded bash
It was double celebrations for Brian Cox and his wife Nicole Ansari-Cox two weeks ago, as the couple marked the actor's 80th birthday and their 25th wedding anniversary.
Married couple reveal they had a 'holiday divorce' opting for separate 10-day trips without each other - and why others should do the same this summer
Lev Baker and Mia Kim, a married couple, met in Poland, while they were both solo travelling - but even nowadays travel without each other in tow.
Shania Twain leaves fans delighted as she performs intimate gig for just 200 fans in a London pub
Shania Twain left fans delighted as she performed an intimate gig for just 200 fans in a London pub this weekend.
Death of schoolboy, 12, sparks Brentwood murder investigation
Two people have been arrested after the death of a 12-year-old boy in Brentwood
Bill Gates's embarrassing secrets revealed by Epstein-linked mistress who Melinda HATED
Dr. Melanie S. Walker started working for Gates's foundation in 2006 after striking up a relationship with Microsoft exec Steven Sinofsky.
'Godzilla' fat jab tackles arthritis, sleep apnoea and cuts heart risk - as study reveals dramatic weight loss
As well as helping patients shed pounds, the treatment improved blood sugar control, reduced cardiovascular risk factors and cut knee osteoarthritis pain by around 70 per cent.
Moment Harry Styles forgets the lyrics to his own song and is left apologising to fans after on stage blunder
Harry Styles was left apologising to fans as he performed this weekend after he forgot the lyrics to his own song in an on-stage blunder.
Single mum left 'stranded' in Gran Canaria after Ryanair seats her two-year-old daughter on her own on flight home
Sophie Lux, who was travelling alone with her son Ronnie, nine, and daughter Scarlett, two, was given separate seats from her children when she booked a flight.
Priti Patel to be joined by author Linda Farrow for Get Witham Reading campaign
Priti Patel's annual literacy campaign Get Witham Reading is marking its 15th anniversary.
Nottingham families call on Starmer to change law so triple killer can be charged with murder
The family members of Nottingham stabbing victims Ian Coates, Barnaby Webber and Grace O'Malley-Kumar said their loved ones' killer 'got away with murder' and are demanding change.