Jessica Alba's divorce from Cash Warren 'complicated' thanks to film career and $640M Honest Company
Alba's money comes not just from her high-profile movie career which includes films such as Honey, but it also is from her success as the founder of Honest Company.
Evidence bombshell for Kentucky sheriff 'who shot judge in chambers after sex scandal'
The defense team representing a Kentucky sheriff who allegedly shot a judge in his chambers last year has made a shocking admission.
Deaf Essex woman with rare condition 'didn't feel safe' doing every day things
She opened up about some scary events that led her to feel 'unsafe' doing things people do every day
Pennsylvania woman's heinous excuse after falsely accusing man she never met of attempted rape and kidnapping
A 20-year-old Pennsylvania woman gave a shocking excuse for the reason she falsely accused a man of attempting to kidnap and rape her.
Taylor Swift surfaces with family in NYC after Justin Baldoni 'brought her up' in Blake Lively lawsuit
The sighting comes amid claims she was was left 'perplexed' by Justin Baldoni 's supposed claim that Blake Lively enlisted her to 'pressure' him in his explosive new lawsuit.
1927 commercial property in heart of town set to be auctioned next month
The auction will conclude on February 6.
The long lost Essex pub with a chillingly dark past still immortalised by a famous roundabout
The roundabout still carries the name of the pub
Spanish star Carlos Alcaraz vows to get a tattoo of a kangaroo after the Australia Open - on one HUGE condition
Spaniard Carlos Alcaraz is planning on leaving Australian with a permanent memento, but there is one big condition behind his pledge to get a tattoo of a kangaroo
Novak Djokovic warns drunk Australian Open fans are over-stepping the mark after all-time heckler sledge
Novak Djokovic has warned fans are overstepping the mark after riding an emotional rollercoaster through to a mind-boggling 67th grand slam second-week appearance
Why Novak Djokovic can't get enough of Danielle Collins' bullish behaviour at the Australian Open - 'big fan'
Tennis superstar Novak Djokovic has declared he is a 'big fan' of Australian Open villain Danielle Collins as unruly crowd behaviour threatens to escalate at Melbourne Park.
Clock ticking for TikTok as US Supreme Court upholds ban
With Biden reportedly planning to skirt enforcement and kick the can to Trump, this saga might still not be over
Updated The US Supreme Court has upheld a law requiring TikTok to either divest from its Chinese parent ByteDance or face a ban in the United States. The decision eliminates the final legal obstacle to the federal government forcing a shutdown of the platform for US users on January 19.…
OpenAI Has Created an AI Model For Longevity Science
OpenAI has developed a language model designed for engineering proteins, capable of converting regular cells into stem cells. It marks the company's first venture into biological data and demonstrates AI's potential for unexpected scientific discoveries. An anonymous reader quotes a report from MIT Technology Review:
Last week, OpenAI CEO Sam Altman said he was "confident" his company knows how to build an AGI, adding that "superintelligent tools could massively accelerate scientific discovery and innovation well beyond what we are capable of doing on our own." The protein engineering project started a year ago when Retro Biosciences, a longevity research company based in San Francisco, approached OpenAI about working together. That link-up did not happen by chance. Sam Altman, the CEO of OpenAI, personally funded Retro with $180 million, as MIT Technology Review first reported in 2023. Retro has the goal of extending the normal human lifespan by 10 years. For that, it studies what are called Yamanaka factors. Those are a set of proteins that, when added to a human skin cell, will cause it to morph into a young-seeming stem cell, a type that can produce any other tissue in the body. [...]
OpenAI's new model, called GPT-4b micro, was trained to suggest ways to re-engineer the protein factors to increase their function. According to OpenAI, researchers used the model's suggestions to change two of the Yamanaka factors to be more than 50 times as effective -- at least according to some preliminary measures. [...] The model does not work the same way as Google's AlphaFold, which predicts what shape proteins will take. Since the Yamanaka factors are unusually floppy and unstructured proteins, OpenAI said, they called for a different approach, which its large language models were suited to. The model was trained on examples of protein sequences from many species, as well as information on which proteins tend to interact with one another. While that's a lot of data, it's just a fraction of what OpenAI's flagship chatbots were trained on, making GPT-4b an example of a "small language model" that works with a focused data set.
Once Retro scientists were given the model, they tried to steer it to suggest possible redesigns of the Yamanaka proteins. The prompting tactic used is similar to the "few-shot" method, in which a user queries a chatbot by providing a series of examples with answers, followed by an example for the bot to respond to. Although genetic engineers have ways to direct evolution of molecules in the lab, they can usually test only so many possibilities. And even a protein of typical length can be changed in nearly infinite ways (since they're built from hundreds of amino acids, and each acid comes in 20 possible varieties). OpenAI's model, however, often spits out suggestions in which a third of the amino acids in the proteins were changed. "We threw this model into the lab immediately and we got real-world results," says Retro's CEO, Joe Betts-Lacroix. He says the model's ideas were unusually good, leading to improvements over the original Yamanaka factors in a substantial fraction of cases.
Read more of this story at Slashdot.
Primark's adorable Hello Kitty pyjamas that shoppers say are 'too cute'
They are both adorable and very comfortable
British fishing boat accused of 'life-threatening attack on French ship using grappling hooks' in escalation of 'scallop wars'
Officials across the Channel claimed the vessel had cut one of the trawler's cables in a deliberate attack in the early hours of January 15 between Brighton and Dieppe.
Labour gives up plan to replace decrepit NHS hospitals because Wes Streeting 'can't figure out how to fund the project' - leaving patients at risk from crumbling buildings
Labour is set to scrap plans to replace decrepit NHS Hospitals as Health Secretary Wes Streeting admitted he couldn't work out how to fund the project.
Jimmy Mizen's mother slams his killer as 'heartless' after drill rapper who shamelessly boasted about violent murder of altar boy in lyrics is hauled back to jail for breaching parole
Jake Fahri, also known as drill rapper TEN, was handed a life sentence in 2009 with a minimum term of 14 years for killing Jimmy.
Woman horrified by 'catfish' London accommodation with mysterious 'brown spots' on the bed and a VERY impractical entrance
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Distraught father screamed 'my boy, my boy' after his four-year-old son was run over by neighbour's minibus
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Record numbers of British millionaires ditch UK over fears Labour's tax plans are damaging the economy
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Chloe Madeley gives a relationship status update as she opens up about wanting more kids after it was revealed ex-husband James Haskell is dating mother-of-two Helen Barclay
The TV personality, 37, split from the rugby player, 39, with whom she shares two-year-old daughter Bodhi, in October 2023 after 10-years together