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Focused Sound Energy Holds Promise For Treating Cancer, Alzheimer's and Other Diseases

2 weeks 5 days ago
An anonymous reader quotes a report from the Conversation: Sound waves at frequencies above the threshold for human hearing are routinely used in medical care. Also known as ultrasound, these sound waves can help clinicians diagnose and monitor disease, and can also provide first glimpses of your newest family members. And now, patients with conditions ranging from cancer to neurodegenerative diseases like Alzheimer's may soon benefit from recent advances in this technology. I am a biomedical engineer who studies how focused ultrasound -- the concentration of sound energy into a specific volume -- can be fine-tuned to treat various conditions. Over the past few years, this technology has seen significant growth and use in the clinic. And researchers continue to discover new ways to use focused ultrasound to treat disease. [...] Research on focused ultrasound has primarily focused on the most devastating and prevalent diseases, such as cancer and Alzheimer's disease. However, I believe that further developments in, and increased use of, focused ultrasound in the clinic will eventually benefit patients with rare diseases. One rare disease of particular interest for my lab is cerebral cavernous malformation, or CCM. CCMs are lesions in the brain that occur when the cells that make up blood vessels undergo uncontrolled growth. While uncommon, when these lesions grow and hemorrhage, they can cause debilitating neurological symptoms. The most common treatment for CCM is surgical removal of the brain lesions; however, some CCMs are located in brain areas that are difficult to access, creating a risk of side effects. Radiation is another treatment option, but it, too, can lead to serious adverse effects. We found that using focused ultrasound to open the blood-brain barrier can improve drug delivery to CCMs. Additionally, we also observed that focused ultrasound treatment itself could stop CCMs from growing in mice, even without administering a drug. While we don't yet understand how focused ultrasound is stabilizing CCMs, abundant research on the safety of using this technique in patients treated for other conditions has allowed neurosurgeons to begin designing clinical trials testing the use of this technique on people with CCM. With further research and advancements, I am hopeful that focused ultrasound can become a viable treatment option for many devastating rare diseases.

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Western Executives Shaken After Visiting China

2 weeks 5 days ago
mspohr shares a report from Futurism: Western automotive and green energy executives who visit China are returning humbled -- and even terrified. As The Telegraph reports, the executives are warning that the country's heavily automated manufacturing industry could quickly leave Western nations behind, especially when it comes to electric vehicles. "We are in a global competition with China, and it's not just EVs," Ford CEO Jim Farley told The Verge last month. "And if we lose this, we do not have a future at Ford." Some companies are giving up on new initiatives altogether, with the founder of mining company Fortescue, Andrew Forrest, claiming that his recent trip to China led to him abandoning attempts to produce EV powertrains in-house. "There are no people -- everything is robotic," he told The Telegraph. Other executives recalled touring "dark factories" that don't even need to keep the lights on, as most work is being done around the clock by robots. "You get this sense of a change, where China's competitiveness has gone from being about government subsidies and low wages to a tremendous number of highly skilled, educated engineers who are innovating like mad," British energy supplier Octopus CEO Greg Jackson told the newspaper. According to recent figures by the International Federation of Robotics, China has deployed orders of magnitude more industrial robots than Germany, the US, and the UK.

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Norway Says 'Mission Accomplished' On Going 100% EV, Proposes Incentive Changes

2 weeks 5 days ago
Norway has effectively achieved its 2025 goal of 100% electric new car sales, prompting the government to declare "mission accomplished" and propose scaling back EV tax exemptions to reflect a mature market. "We have had a goal that all new passenger cars should be electric by 2025, and ... we can say that the goal has been achieved," announced Finance Minister Jens Stoltenberg. Electrek reports: With the finish line in sight, the Norwegian government is now fine-tuning its approach. The current incentive program maintains the crucial VAT exemption for EVs, but only up to a purchase price of 500,000 Norwegian kroner (approximately $49,000 USD). This move is designed to target more expensive, luxury EVs, ensuring that the incentive benefits a broader range of consumers. However, the latest budget proposal aims to reduce the EV tax exemption to vehicles costing 300,000 Norwegian kroner (~30,000 USD). This would apply for 2026, and then the tax exemption would completely end in 2027. Additionally, the government plans to increase taxes on new gasoline and diesel cars, further widening the cost gap between polluting and zero-emission vehicles. However, the proposal still needs to be adopted by Norway's government, and there is some opposition. EV associations are advocating for a more extended phase-out period to ensure that the adoption rate doesn't decline.

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