US oil titan fires a quarter of its staff as jobs bloodbath spreads from retail and technology
The oil company is set to layoff up to 25 percent of its workforce in an extravagant cost-cutting drive.
Has Sydney Sweeney already been cancelled? Romance with Taylor Swift's arch-nemesis Scooter Braun comes after backlash against Hollywood darling from the woke mob
The pair reportedly met while attending the Venice wedding of billionaire Jeff Bezos and Lauren Sanchez in June, and sources claimed the music mogul has been 'pursuing' her ever since.
DAILY MAIL COMMENT: A new politics is beginning. Everything we knew and accepted as normal is dissolving and crumbling. It's time for all the talents on the Right to come together to sweep away this lamentable excuse for a government
When a former Cabinet Minister and long-term MP quits the party she has served for more than a quarter of a century, you may be sure there is something seriously amiss with that party.
Starmer is 'prepared to sack Angela Rayner' if she broke rules after lawyers accused her of making them 'a scapegoat' - as report into tax fiasco is due TODAY
Deputy Prime Minister Angela Rayner is skating on thin ice as the ministerial ethics adviser prepares to deliver his verdict as soon as today.
Nancy Mace demands Prince Andrew be locked up and thrown in 'cold dark cell' following heart-wrenching Epstein meetings
Firebrand Nancy Mace is demanding that Prince Andrew be thrown in prison for his alleged involvement with Jeffrey Epstein.
Trump ignites culture war with extraordinary plan to ban transgender Americans from owning guns
President Donald Trump's Justice Department could take a huge step to address gun violence that goes against decades of precedent set by previous Republican administrations.
Amanda Anisimova keeps American dream alive at US Open with stunning late-night win over Naomi Osaka to reach final
MATTHEW LAMBWELL ON ARTHUR ASHE: At 12.54am on Friday morning, at the end of a pulsating and exhausting night session, Amanda Anisimova surged past Naomi Osaka.
The faces of eight people Essex Police want to identify in Epping Bell Hotel disorder investigation
It's part of an investigation into incidents of disorder at protest events in Epping
Lena Dunham's 'insane' new memoir slammed by fans who resurface star's 'sexual abuse' controversy on sibling
Lena Dunham has been slammed for announcing a new memoir - 11 years after her first tell-all sparked claims she had molested her sibling.
Shock twist as new footage shows Cowboys superstar Dak Prescott SPIT at Eagles star FIRST... before taking one in the face
Carter, the best player on the Super Bowl champions' defense, approached the Cowboys QB before the first snap of the game and appeared to spit in his direction.
Conjoined twins Abby and Brittany Hensel share new photos after breaking silence over newborn baby
Abby and Brittany Hensel shared never-before-seen wedding photos, days after breaking their silence on viral images of the duo carrying a newborn baby.
Venezuelan fighter jets fly over US Navy destroyer in 'show of force' days after US missile strike on 'drug boat'
Two Venezuelan F-16 fighter jets flew over a US Navy destroyer in the southern Caribbean sea as a show of force on Thursday, the Department of Defense said.
Talk TV host and former Tory hoping for return to Essex politics, are switching to Reform UK
The former Tory councillor has his sights on the upcoming Essex mayoral election next year
Crufts award-winning police dog Baloo enjoys heaps of attention in Essex town
A fan-favourite former police dog enjoyed lots of attention and boosting spirits at a community open day.
M25, Dartford Crossing and A12 road closures in Essex this weekend
A few motorway closures will impact Essex traffic this weekend, according to National Highways England.
M25, Dartford Crossing and A12 road closures in Essex this weekend
A few motorway closures will impact Essex traffic this weekend, according to National Highways England.
HPE Systems Rebound As Juniper Brings A Further Boost
Sales of GPU-accelerated servers are still hurting margins at Hewlett Packard Enterprise, as they are doing at all OEMs and probably the ODMs, too, but the good news is that they will be hurting less and less as sales of beefier and more profitable general purpose servers are on the rise and as sovereign clouds and neoclouds turn to HPE for iron and pay higher unit prices for gear. …
HPE Systems Rebound As Juniper Brings A Further Boost was written by Timothy Prickett Morgan at The Next Platform.
Has a miniature portrait revealed Shakespeare's secret gay lover?
A previously unknown portrait of what could have been William Shakespeare's gay lover has been revealed.
Air Pollution Can Drive Devastating Forms of Dementia, Research Suggests
An anonymous reader quotes a report from The Guardian: Fine-particulate air pollution can drive devastating forms of dementia by triggering the formation of toxic clumps of protein that destroy nerve cells as they spread through the brain, research suggests. Exposure to the airborne particles causes proteins in the brain to misfold into the clumps, which are hallmarks of Lewy body dementia, the second most common form of dementia after Alzheimer's disease. The finding has "profound implications" for preventing the neurodegenerative disorder, which affects millions worldwide, with scientists calling for a concerted effort to improve air quality by cutting emissions from industrial activity and vehicle exhausts, improving wildfire management and reducing wood burning in homes.
The researchers began by analyzing hospital records of the 56.5 million US Medicare patients. They looked at those who were admitted for the first time between 2000 and 2014 with the protein damage. Armed with the patients' zip codes, the scientists estimated their long-term exposure to PM2.5 pollution, airborne particles that are smaller than 2.5 thousandths of a millimeter. These can be inhaled deep into the lungs and are found in the bloodstream, brain and other organs. They found that long-term exposure to PM2.5 raised the risk of Lewy body dementia, but had less of an impact on rates of another neurodegenerative brain disease that is not driven by the toxic proteins. Lewy bodies are made from a protein called alpha-synuclein. The protein is crucial for healthy brain functioning, but can misfold in various ways to produce different kinds of harmful Lewy bodies. These can kill nerve cells and cause devastating disease by spreading through the brain.
To see if air pollution could trigger Lewy bodies, the team exposed mice to PM2.5 pollution every other day for 10 months. Some were normal mice, but others were genetically modified to prevent them making alpha-synuclein. The results were striking: in normal mice, nerve cells died off, leading to brain shrinkage and cognitive decline. The genetically modified mice were largely unaffected. Further work in mice showed that PM2.5 pollution drove the formation of aggressive, resilient and toxic clumps of alpha-synuclein clumps that looked very similar to Lewy bodies in humans. Although the work is in mice, the findings are considered compelling evidence. The work has been published in the journal Science.
Read more of this story at Slashdot.
Carer stole £10k from dementia patient and blew it on KFC, Netflix and sunbeds while the victim told her family 'something bad' had happened but she could not remember what
A callous carer who stole more than £10k from the wife of a bedridden pensioner she was supposed to be looking after, before blowing the money on KFC, Netflix and sunbeds has been jailed.