10ft high wall to be built along Cape Town's notorious 'Hell Run' motorway to protect tourists from violent gangs
The stretch of the N2 highway has gained a grim reputation in recent years, with repeated smash-and-grab attacks and ambush-style robberies leading to multiple deaths.
Former Corrie star Richard Fleeshman marries glamorous Dutch actress in an 'unforgettable' country wedding
Richard Fleeshman has announced he has married Dutch actress Celinde Schoenmaker, four years after they got engaged.
Joe Jonas goes Instagram official with his 'caliente' girlfriend Tatiana Gabriela during Puerto Rico vacation
The 36-year-old boybander uploaded a nine-minute YouTube vlog of their adventures in San Juan
Back to the backstop? Starmer 'considering Theresa May-like deal to align Britain with EU's single market' in latest Brexit reversal
The Prime Minister is said to be looking at proposals that would see UK firms follow Brussels rules with no say on how they are drawn up.
Pancreatic Cancer mRNA Vaccine Shows Lasting Results In Early Trial
NBC News reports on a 16-person clinical trial of "personalized messenger RNA vaccines" which use the immune system to fight cancer cells. "The goal is not to eliminate existing tumors, but instead to stamp out lingering, undetected cancer cells, and later any new cells that form before they can cause a recurrence."
Patients still have surgery to remove tumors. After that, the mRNA vaccines are personalized for each individual using genetic material taken from their unique tumor cells. In the clinical trial, after getting the vaccine, the patients also received chemotherapy, which is standard post-op treatment for operable pancreatic cancer... [The article notes that less than 13% of people diagnosed with pancreatic cancer live for more than five years, making it "one of the deadliest cancers."]
[E]xperts have long believed that people with pancreatic cancer could not generate an immune response against tumors. But after nine doses of the personalized vaccine, [clinical trial participant Donna] Gustafson is one of eight people in the 16-person Phase 1 trial who did just that, producing an army of immune cells called T cells that seek out and destroy tumor cells... [Dr. Vinod Balachandran, a vaccine center director who is leading the trial, said] it was unclear whether the immune response would last and lead to the patients living longer... New data collected during the trial's six-year follow-up period shows that it may. Those findings will be presented Monday at the American Association for Cancer Research's annual meeting in San Diego. Six years after treatment, Gustafson and six others who responded to the treatment are still alive...
More research is still needed. Genentech and BioNTech, the two drugmakers behind the vaccine, have already launched a larger Phase 2 clinical trial... Another team is working on an off-the-shelf vaccine that targets a protein called KRAS that is present in as many as 90% of pancreatic cancers. In a small, early trial, about 85% of the participants mounted an immune response to the protein.
Read more of this story at Slashdot.
Top NFL prospect Zachariah Branch arrested in Georgia just days before draft begins
Athens Clarke County police arrested him for obstructing public sidewalks/streets-prowling and obstruction of a law enforcement officer, it has emerged.
I was in the Navy's most elite force and faced grueling 24-hour drills... here are three at-home challenges to try if you want to put yourself to the ultimate test
Marcus Capone was a member of the US Navy's most elite force for 13 years. Here's his advice on how to train like a recruit.
No invite for Starmer? Rayner and Burnham spotted holding late-night meeting in Manchester fuelling talk of a leadership challenge days after pair were all smiles with PM
Greater Manchester mayor Mr Burnham was seen leaving Ms Rayner's constituency home in the city late on Friday, days after they played happy families with the PM on the campaign trail.
Now ministers claim Starmer would have U-turned on making Mandelson UK's top diplomat if told of peer's vetting failure - as PM is branded 'unfit to govern'
They leapt to the defence of the Prime Minister as he faced ever-increasing questions and pressure over the revelations that experts who deemed Mandelson a security risk were over-ruled.
Influencer, 38, is found dead in lake after going missing during ironman triathlon
Brazilian Mara Flavia Araujo was pulled from Lake Woodlands on the outskirts of Houston, Texas, on Saturday at around 9.30am.
Motorola Sues Social Media Platforms and Creators in India
"Motorola has filed a lawsuit in India against social media platforms and content creators," reports TechCrunch, "over posts it alleges are defamatory..."
The lawsuit, filed in a Bengaluru court and obtained by TechCrunch, names platforms such as X, YouTube, and Instagram along with dozens of content creators, and seeks takedown of the content as well as broader restraint on what it describes as false or defamatory material related to the company's devices. In its over 60-page filing, Motorola has sought a permanent injunction restraining the defendants from publishing or sharing what it describes as false or defamatory content about its products, including reviews, videos, comments, and boycott campaigns.
The complaint cites hundreds of posts across platforms, including videos alleging device issues and phones catching fire. But it is also targeting unfavorable product reviews and user commentary that the company alleges are false or defamatory. In a statement after publication, a Motorola spokesperson said it had initiated legal action "in the interest of public safety" against what it described as demonstrably false claims that its devices had exploded or caught fire.
One online creator told TechCrunch "they expect more such legal action in the future, as evolving rules around online content increase liability for creators and platforms — a trend reflected in recently proposed changes to India's IT rules aimed at tightening oversight of online content."
A Motorola spokesperson "said the company did not seek to suppress legitimate reviews or criticism and was reviewing the scope of the proceedings, adding that it apologized to creators affected inadvertently."
Read more of this story at Slashdot.
At 63 I was so ashamed of snoring I forced myself to stay awake all night - now I've discovered this miracle cure I'm looking forward to finally sleeping soundly
I've tried a lot of snoring 'cures'. Special curved pillows, nasal dilators, a tennis ball taped to the back of a T-shirt, mouth taping, humidifiers and dehumidifiers, open windows in winter
Jack Whitehall and Roxy Horner's extravagant wedding at impressive venue with VIP guests
The comedian married the Essex model this weekend
Glamorous Iranian woman living high life in Los Angeles is arrested for 'trafficking deadly drones and bombs for Tehran'
Shamim Mafi, 44, was arrested at Los Angeles International Airport on Saturday night for allegedly trafficking deadly drones and bombs for Tehran.
It looks like the epitome of luxury living but no one wants to move into tower on notorious plot in Miami
A Dubai developer behind a controversial luxury condo project has failed to sell a single unit more than a year after the project was first touted.
Nevada Police Can Now Track Cellphones Without a Warrant
"Nevada quietly signed an agreement earlier this year with a company that collects location data from cellphones, allowing police to track a device virtually in real time," reports the Associated Press. "All without a warrant."
The software from Fog Data Science, adopted this January in Nevada through a Department of Public Safety contract, pulls information from smartphone apps in order to let state investigators identify the location of mobile devices. The state is allowed more than 250 queries a month using the tool, which allows officers to track a device's location over long stretches of time and enables them to see what Fog calls "patterns of life," according to company documents from 2022. It can help them deduce where and when people work and live, with whom they associate and what places they visit, according to privacy experts... Traditionally, police must obtain a warrant from a judge to access cellphone location information — a process that can take days or weeks. And while cellphone users may be aware that they are sharing their location through apps such as Google Maps, critics say few are aware that such information can make its way to police...
Other agencies in Nevada have been known to use technology similar to Fog. In 2013, Las Vegas Metropolitan Police Department acquired something known as a cell-site simulator that mimics cellphone towers and can sweep up signals from entire areas to track individuals, with some models capable of intercepting texts and calls. Police have not released detailed information about the technology since then.
"Police in other states have said the technology (and its low price tag) has helped expand investigatory capacity," the article adds.
But it also points out that Fog Data Science has a web page letting individuals opt out of all their data sets.
Read more of this story at Slashdot.
Amanda Knox accused of 'cashing in on Meredith Kercher's memory' as she poses for selfies at Tower Bridge - while publicising documentary a stone's throw away from where murder victim was raised
Amanda Knox is pictured in London for the first time as she crudely promotes her new film revisiting the murder of British student Meredith Kercher. .
Which way should you face in the shower? Scientists finally settle the debate - so, have you been doing it wrong this entire time?
It's something most people do every day without thinking twice about it. But when you step into the shower, do you face toward, or away from the water?
Christina Aguilera looks thinner than ever in plunging black leather gown at Breakthrough Prize Ceremony
Christina Aguilera put her astounding weight loss on full display with a sizzling appearance on the red carpet for Saturday's Breakthrough Prize Ceremony.
Woman behind 'beloved' bookshop retires after 30 years serving community
A beloved Wivenhoe figure has said goodbye after more than 30 years to town’s most popular independent bookshop.