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Scientists Discuss Next Steps to Prevent Dangerous 'Mirror Life' Research

2 months ago
USA Today has an update on the curtailing of "mirror life" research: Kate Adamala had been working on something dangerous. At her synthetic biology lab, Adamala had been taking preliminary steps toward creating a living cell from scratch with one key twist: All the organism's building blocks would be flipped. Changing these molecules would create an unnatural mirror image of a cell, as different as your right hand from your left. The endeavor was not only a fascinating research challenge, but it also could be used to improve biotechnology and medicine. As Adamala and her colleagues talked with biosecurity experts about the project, however, grave concerns began brewing. "They started to ask questions like, 'Have you considered what happens if that cell gets released or what would happen if it infected a human?'" said Adamala, an associate professor at the University of Minnesota. They hadn't. So researchers brought together dozens of experts in a variety of disciplines from around the globe, including two Nobel laureates, who worked for months to determine the risks of creating "mirror life" and the chances those dangers could be mitigated. Ultimately, they concluded, mirror cells could inflict "unprecedented and irreversible harm" on our world. "We cannot rule out a scenario in which a mirror bacterium acts as an invasive species across many ecosystems, causing pervasive lethal infections in a substantial fraction of plant and animal species, including humans," the scientists wrote in a paper published in the journal Science in December alongside a 299-page technical report... [Report co-author Vaughn Cooper, a professor at the University of Pittsburgh who studies how bacteria adapt to new environments] said it's not yet possible to build a cell from scratch, mirror or otherwise, but researchers have begun the process by synthesizing mirror proteins and enzymes. He and his colleagues estimated that given enough resources and manpower, scientists could create a complete mirror bacteria within a decade. But for now, the world is probably safe from mirror cells. Adamala said virtually everyone in the small scientific community that was interested in developing such cells has agreed not to as a result of the findings. The paper prompted nearly 100 scientists and ethicists from around the world to gather in Paris in June to further discuss the risks of creating mirror organisms. Many felt self-regulation is not enough, according to the institution that hosted the event, and researchers are gearing up to meet again in Manchester, England, and Singapore to discuss next steps.

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EditorDavid

AI Tool Usage 'Correlates Negatively' With Performance in CS Class, Estonian Study Finds

2 months ago
How do AI tools impact college students? 231 students in an object-oriented programming class participated in a study at Estonia's University of Tartu (conducted by an associate professor of informatics and a recently graduated master's student). They were asked how frequently they used AI tools and for what purposes. The data were analyzed using descriptive statistics, and Spearman's rank correlation analysis was performed to examine the strength of the relationships. The results showed that students mainly used AI assistance for solving programming tasks — for example, debugging code and understanding examples. A surprising finding, however, was that more frequent use of chatbots correlated with lower academic results. One possible explanation is that struggling students were more likely to turn to AI. Nevertheless, the finding suggests that unguided use of AI and over-reliance on it may in fact hinder learning. The researchers say their report provides "quantitative evidence that frequent AI use does not necessarily translate into better academic outcomes in programming courses." Other results from the survey: 47 respondents (20.3%) never used AI assistants in this course. Only 3.9% of the students reported using AI assistants weekly, "suggesting that reliance on such tools is still relatively low." "Few students feared plagiarism, suggesting students don't link AI use to it — raising academic concerns."

Read more of this story at Slashdot.

EditorDavid