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New Antibiotic Could Be a Breakthrough in Treatment for Killer TB, Trial Suggests

1 month 1 week ago
A new treatment for tuberculosis could boost cure rates and shorten the time needed to treat the disease by months, trial results suggest. The Guardian: Globally, an estimated 10.7 million people fell ill with TB last year and 1.23 million died from it. In its annual report on tuberculosis, launched last week, the World Health Organization said it remained a "major global public-health problem" and the leading infectious cause of death. [...] Sorfequiline, a new antibiotic, showed stronger action against the deadly bacteria than existing treatments, with a comparable safety profile, researchers from the TB Alliance told the Union Conference on Lung Health in Copenhagen on Wednesday. The trial involved 309 people across 22 sites in South Africa, the Philippines, Georgia, Tanzania and Uganda, with different dose regimens. All participants had "drug-sensitive" tuberculosis, meaning a standard cocktail of drugs can safely treat them but researchers believe TB infections that are resistant to standard treatment could also be helped. The trial suggested a sorfequiline-based regimen could be used for anyone testing positive, said Dr Maria Beumont, vice-president of TB Alliance.

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Ultra-Processed Food is Global Health Threat, Researchers Warn

1 month 1 week ago
Action is needed now to reduce ultra-processed food (UPF) in diets worldwide because of their threat to health, say international experts in a global review of research. From a report: They say the way we eat is changing - with a move away from fresh, whole foods to cheap, highly-processed meals - which is increasing our risk of a range of chronic diseases, including obesity and depression. Writing in The Lancet, the researchers say governments need "to step up" and introduce warnings and higher taxes on UPF products, to help fund access to more nutritious foods. [...] This review of evidence on the impact of UPFs on health, carried out by 43 global experts and based on 104 long-term studies, suggests these foods are linked to a greater risk of 12 health conditions. These include type 2 diabetes, cardiovascular disease, kidney disease, depression and dying prematurely from any cause.

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Europe's Cookie Nightmare is Crumbling

1 month 1 week ago
The EU's cookie consent policies have been an annoying and unavoidable part of browsing the web in Europe since their introduction in 2018. But the cookie nightmare is about to crumble thanks to some big proposed changes announced by the European Commission today. From a report: Instead of having to click accept or reject on a cookie pop-up for every website you visit in Europe, the EU is preparing to enforce rules that will allow users to set their preferences for cookies at the browser level. "People can set their privacy preferences centrally -- for example via the browser -- and websites must respect them," says the EU. "This will drastically simplify users' online experience." This key change is part of a new Digital Package of proposals to simplify the EU's digital rules, and will initially see cookie prompts change to be a simplified yes or no single-click prompt ahead of the "technological solutions" eventually coming to browsers. Websites will be required to respect cookie choices for at least six months, and the EU also wants website owners to not use cookie banners for "harmless uses" like counting website visits, to lessen the amount of pop-ups.

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