What King and Conqueror gets wrong about 1066: Biggest untruths in James Norton's Battle of Hastings drama revealed
Those who hoped that new TV drama King and Conqueror might at least accurately depict what we do know about 1066 have been left disappointed.
Moment Notting Hill Carnival revellers brawl as police arrest 400 but hail facial recognition for reducing violence at festival... with just two stabbings
Footage filmed inside a Tube station shows a man in a brightly coloured carnival costume scuffling with a group of other revellers.
Man found dead near Chelmsford city centre pub
He was sadly pronounced dead at the scene
Stacey Solomon QUITS Loose Women after 13 years amid ITV's daytime telly bloodbath with heavy budget cuts and job losses
Stacey Solomon has quietly quit Loose Women after 13 years on the panel, the Daily Mail can reveal.
Girl, 13, 'raped and murdered by teen boy' had 'suffered multiple cardiac arrests' before her death, inquest hears
Casey-Louise Horrocks, a schoolgirl from Oldham, Greater Manchester, was found 'unresponsive' in the bedroom of a 16-year-old boy in Huddersfield, West Yorkshire, on August 11.
Ethiopian asylum seeker staying in Epping migrant hotel 'sexually assaulted girl of 14' and told her they could 'make lovely Jamaican babies', court hears
Ethiopian national Hadush Gerberslasie Kebatu, 38, allegedly put his hand on the schoolgirl's thigh, tried to kiss her and said he wanted to have a baby with her, Chelmsford Magistrates' Court heard.
Frances Tiafoe delivers brutal verdict on Carlos Alcaraz's new drastic US Open haircut
Despite arriving in New York with his signature thick, flowing locks on Saturday, just two days later former champion Carlos Alcaraz debuted a wildly different hairstyle on Monday.
Man arrested in mid Essex police raid as suspected drugs and money found at home
A MAN has been arrested after suspected Class A and B drugs were found during a police raid in Witham.
Two scrubs, one Starship: Third time lucky for SpaceX?
We've going to Mars! Oh no – anvil clouds!
Elon Musk's monster rocket, Starship, remains firmly on the launchpad after two scrubs in a row, first due to an oxygen leak and then some clouds.…
AbbVie Targets Psychedelic-Based Depression Drug Market With $1.2 Billion Deal
An anonymous reader quotes a report from Reuters: AbbVie will buy an experimental depression drug from partner Gilgamesh Pharmaceuticals for up to $1.2 billion, the companies said on Monday, seeking to access a fast-growing market for psychedelic-based treatments. The deal is the latest in the more than $20 billion AbbVie has spent on acquisitions since 2023 for drugs that can drive growth as its flagship rheumatoid arthritis treatment, Humira, lost patent protection. The companies had signed a partnership last year to develop therapies for psychiatric disorders, with privately held Gilgamesh set to receive up to $1.95 billion in option fees and milestone payments. The deals with Gilgamesh, which is also developing treatments for anxiety and post-traumatic stress disorder, also launch AbbVie into the race to develop psychedelic compounds for psychiatric conditions -- a potential $50 billion market, according to Cantor Fitzgerald analyst Josh Schimmer.
The deal, which includes an upfront payment and development milestones, could also bolster AbbVie's neurological conditions portfolio after its experimental schizophrenia drug, which it gained access to through an $8.7 billion purchase of Cerevel Therapeutics, failed in two mid-stage studies last year. Gilgamesh's lead candidate for depression, bretisilocin, activates the 5-HT2A serotonin receptor -- also targeted by classic psychedelics such as psilocybin, found in magic mushrooms, and LSD. The companies said bretisilocin has been shown to exert a shorter duration of psychoactive experience while retaining an extended therapeutic benefit in early and mid-stage studies. AbbVie will advance the drug into late-stage studies. "Large Pharma has been less active exploring psychedelic compounds due to potential regulatory concerns ... making today's deal more significant," said BMO Capital Markets analyst Evan Seigerman.
Read more of this story at Slashdot.
Essex cocaine dealer ordered to pay back £40k of profits or face a further 4 years behind bars
He was the head of a crime gang that shipped cocaine across Essex in bulk
Essex mum paid £3.5k after police officers handled lingerie and sex toys during raid
Nichola Corr, 51, of north Essex, says Suffolk Police conducted a search of her home as part of a drugs investigation
Revealed: How much Meghan Markle's Netflix wardrobe is worth as she pairs designer dresses with lavish jewellery including £56k pinky ring
Meghan Markle has become synonymous with luxury fashion, often stepping out in looks from iconic designers. And in season two of her Netflix series, the Duchess once again delivered.
Rachel Reeves confirms MP Torsten Bell will help with Budget prep - here's seven tax ideas he's had in the past...
He ran the Resolution Foundation think tank, which proposed that the triple lock be scrapped and inheritance tax be overhauled.
The truth about 'Saint' Peter Andre: Katie Price was 'trapped' by her fame-hungry ex, friends tell KATIE HIND, as they reveal why singer's vile comments about Harvey show who he really is behind 'great guy' image
It was at the baggage reclaim carousel inside Malaga airport I first saw the toll Peter Andre had taken on Katie Price. She was heartbroken at how he had ended their marriage.
Sam Faiers opens up on real reason she quit reality TV as she makes return to screens
Sam Faiers has revealed the real reason she quit reality TV back in 2021 as she makes her grand return to the small screen alongside her sister Billie Shepherd
France opens inquiry into streaming platform Kick days after online star died on camera following 'ten days of torture and humiliation'
The probe, announced on Tuesday, will examine whether Kick 'knowingly' broadcast 'videos of deliberate attacks on personal integrity' after the death of Raphael Graven.
Syrian refugee who sexually assaulted teenager before claiming being jailed for it would breach his human rights is locked up
Hassan Abou Hayleh, 40, attacked a 19-year-old girl after finding her sitting alone on a kerb in Weymouth, Dorset, as she waited for her father to give her a lift home.
Stacey Solomon denies reports she's 'quit' ITV's Loose Women
ITV's Loose Women star Stacey Solomon has denied that she has left the daytime show
Ulrika Jonsson criticises Serena Williams for 'forcing feminism back by several steps' after tennis player revealed recent weight-loss was down to skinny jab
The TV presenter, 58, shared her concerns for 'impressionable young women' and said the endorsement was a 'betrayal of everything Serena has stood for.'