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The eight-carriage train came off the line between Haywards Heath and Lewes at around 3.54pm this afternoon, with services set to be cancelled until 10pm.

He tried to arrange to sexually abuse two young children aged four years and four months - but he was speaking to an undercover police officer

In total, 34 candidates stood in the 2024 Clacton by-election, which was comfortably won by Nigel Farage.

In total, 34 candidates stood in the 2024 Clacton by-election, which was comfortably won by Nigel Farage.

A total of 34 candidates were standing in the by-election

The Reform UK leader was one of 34 candidates who ran in a by-election which was not contested by the other major parties.

The Reform UK leader was one of 34 candidates who ran in a by-election which was not contested by the other major parties.

Nigel Farage has won the Clacton by-election after he triggered it by resigning as MP for the Essex constituency earlier this year.

Nigel Farage has won the Clacton by-election after he triggered it by resigning as MP for the Essex constituency earlier this year.

His main opponents were Count Binface and an actor-turned-politician

The future of the plans are set to be discussed

It has been reported that Essex Police did not tell Mr Farage or any other candidate not to attend the count

Nicole Kidman was 23 when she exchanged vows with Cruise, 28, in 1990, the year she landed her Hollywood breakthrough acting alongside him in Days of Thunder.

Colin Calvert and his wife Anna say they have faced black mould, subsidence and rising damp

Four men were drugged when glasses of wine were spiked with a powerful sedative so the two defendants could take money from them. Two of the victims died.

The baby boy, who was born on Wednesday morning in Texas, is now in custody of his biological parents. The couple had previously demanded the surrogate, McKenna West, have an abortion.

It means Britons face decades more misery, with painfully long waits for routine care, such as hip and knee replacements.

Andy Burnham's vow to bring down the cost of living was in tatters yesterday after the water regulator announced bills will rise again for more than 30million people.

An anonymous reader quotes a report from The Guardian: Miniature human organs and other tissues are to be grown from NHS patients' cells in a drive to improve medicine testing and reduce the number of animals used in drug development. Scientists will use the clumps of tissue to learn how diseases vary between patients, helping them identify which treatments are best for different people based on the particular pathology underlying their condition. The move marks a shift away from the traditional use of animals as models for human disease, towards what researchers believe will be more accurate and reliable tests based directly on human tissues. Researchers have been growing tiny clumps of human organs, known as organoids, for more than a decade. Tests show that pieces smaller than a millimeter can mirror key features of full-scale organs and tissues, including how they falter with disease and respond to drugs. Armed with organoids grown from diseased human tissues, scientists can investigate whether new drug candidates reverse pathological changes in all or a subset of patients, and quickly identify ineffective drugs early in the process. Historically, more than 90% of drugs that clear animal testing go on to fail in human trials, raising questions about the value of the tests. US and European medicines regulators now encourage other approaches if available. "It's going to have a major impact on the numbers of animals used and the way we develop new drugs in the future," said Matthias Zilbauer, a clinical professor of paediatric gastroenterology at the Cambridge Stem Cell Institute. "We're not saying there won't be any animal use in the near or foreseeable future, because there are still certain issues that cannot be tested in these new models, but the reduction is very real." "A lot of human diseases either do not occur in animals or occur in a different way because they're not human," added Zilbauer. "We want tests and models that can tell us which treatments work, and in what patients, and a mouse cannot tell us that."

Read more of this story at Slashdot.

Intelligence Service says finding domestic threats is harder due to proliferation of toxic content online