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Ageing Accelerates at Around Age 50 - Some Organs Faster Than Others

3 weeks 4 days ago
A new analysis of protein changes across human tissues has identified an aging acceleration point around age 50, with blood vessels showing the most dramatic deterioration. Researchers examined tissue samples from eight body systems in 76 people of Chinese ancestry aged 14 to 68 who died from accidental brain injury, finding age-related increases in 48 disease-associated proteins. Between ages 45 and 55, the most significant shift occurred in the aorta, the body's main artery carrying oxygenated blood from the heart. The team identified one aortic protein that triggers accelerated aging signs when administered to mice. Early aging changes appeared around age 30 in the adrenal gland, which produces various hormones. The study, published in Cell, adds to mounting evidence that aging occurs in waves rather than following a steady progression.

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Windows 11 is a minefield of micro-aggressions in the shipping lane of progress

3 weeks 4 days ago
A better minesweeper is needed. Time for an intervention to save Microsoft from itself

Workflow. Productivity. Enablement. These are the holy words by which software companies sanctify their ever more plunder-hungry Viking raids on enterprise IT coffers. If only they were true. At least Vikings didn’t pretend to be offering monastery renovations and smart haircuts when they turned up.…

Rupert Goodwins