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alternative_right shares a report from ScienceAlert: If you consumed a wild mushroom and suddenly started seeing tiny people around you, you might reasonably assume it contained a familiar psychedelic. But that does not appear to be the case with Lanmaoa asiatica, known locally as jian shou qing, a mushroom species sold in markets in Yunnan, southwestern China. When eaten undercooked, the mushroom can produce vivid visions of miniature people -- not unlike Gulliver on his travels to Lilliput. To try and find out the root cause, University of Utah mycologists Colin Domnauer and Bryn Dentinger sequenced the genomes of 53 mushroom samples from across the wider Lanmaoa genus. And despite the reported hallucinations, they found no close matches to genes associated with psilocybin or ibotenic acid, two well-known mushroom hallucinogens whose biosynthetic pathways were specifically examined in the study. "Biosynthetic gene mining of the L. asiatica genome found no close hits with any genes known in the production of mushroom psychoactive compounds," write the researchers in their published paper. "This supports our hypothesis of the presence of a novel unidentified metabolite responsible for the unique hallucinogenic properties of L. asiatica." [...] Whatever chemical pathways are causing these effects in the brain, the responsible compound appears to be something scientists have not yet identified. [...] By identifying 1,515 corresponding genes across the selected specimens, the researchers obtained a clearer answer to the question of what defines a mushroom species as part of the genus Lanmaoa. There are now 17 recognized species in the genus, including four that haven't been identified before, two of which the researchers specifically named here: Lanmaoa fallax and Lanmaoa carbonilivor. The researchers say the Lanmaoa family and evolutionary tree can now be more fully mapped out, and some existing specimens may need to be reclassified.

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