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Homeowners often dream of returning to their childhood neighbourhood later in life and many young adults aspire to buy in the area where they grew up.

alternative_right shares a report from Phys.Org: In new research published by scientists studying fission yeastâ"a single-celled organism surprisingly similar to human cellsâ"researchers found that caffeine affects aging by tapping into an ancient cellular energy system. A few years ago, the same research team found that caffeine helps cells live longer by acting on a growth regulator called TOR (target of rapamycin). TOR is a biological switch that tells cells when to grow, based on how much food and energy is available. This switch has been controlling energy and stress responses in living things for over 500 million years. But in their latest study, the scientists made a surprising discovery: Caffeine doesn't act on this growth switch directly. Instead, it works by activating another important system called AMPK, a cellular fuel gauge that is evolutionarily conserved in yeast and humans. "When your cells are low on energy, AMPK kicks in to help them cope," explains Dr. Charalampos (Babis) Rallis, Reader in Genetics, Genomics and Fundamental Cell Biology at Queen Mary University of London, the study's senior author. "And our results show that caffeine helps flip that switch." Interestingly, AMPK is also the target of metformin, a common diabetes drug that's being studied for its potential to extend human lifespan together with rapamycin. Using their yeast model, the researchers showed that caffeine's effect on AMPK influences how cells grow, repair their DNA, and respond to stress -- all of which are tied to aging and disease. The study has been published in the journal Microbial Cell.

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The 51-year-old  made global headlines after being embroiled in a scandalous affair with the then-President Bill Clinton.

Taking to TikTok, UK-based Katrina Corfield shared footage of herself making what appears to be a beverage from the 'Refresher' range.

Gareth Leek, 58, was left stunned when planning officials claimed his beloved garden decking was too tall and needed retrospective permission, despite it being in place for eight years.

Jaskarn or 'Jacky' Jhaj, 39, was arrested after paying £111,000 to stage the vile fake event at the fairlytale Sleeping Beauty castle, featuring musicians, a cake and chairs for 'guests'.

Call 999 if you have seen him or know where he is

Fork that - 5k+ times

Anthropic says it won't fix an SQL injection vulnerability in its SQLite Model Context Protocol (MCP) server that a researcher says could be used to hijack a support bot and prompt the AI agent to send customer data to an attacker's email, among other things.…

Where did you GOTO on your vacation? Nowhere. GOTO is considered harmful. Original --Remy

Everybody knows that you should never use "goto" statements. Well, except in one or two rare circumstances that you won't come across anyway. But even when you do come across those situations, they're usually "mirage cases" where there's no need to "goto" anyway. Kinda like today's example, written by Jonathan Rockway's colleague. Of course, the irony here is that the author likely tried to use "continue" as his label, but was forced to abbreviate it to "cont" in order to skirt compiler "reserved words" errors.

while( sysmgr->getProcessCount() != 0 ) { // Yes, I realize "goto" statements are considered harmful, // but this is a case where it is OK to use them cont: //inactivation is not guaranteed and may take up to 3 calls sysmgr->CurrentProcess()->TryInactivate(); if( sysmgr->CurrentProcess()->IsActive() ) { Sleep(DEFAULT_TIMEOUT); goto cont; } /* ED: Snip */ //disconnect child processes if( sysmgr->CurrentProcess()->HasChildProcesses() ) { /* ED: Snip */ } /* ED: Snip */ if( sysmgr->CurrentProcess()->IsReusable() ) { sysmgr->ReuseCurrentProcess(); goto cont; } sysmgr->CloseCurrentProcess(); }

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Drivers should avoid the area where possible

Amazon founder Jeff Bezos has booked out the five-star Aman Venice hotel for three nights to accommodate the high profile guests attending his Italian wedding to Lauren Sanchez this week.

Taylor Swift made a sensational return to the stage for the first time since the end of the Eras Tour at a concert hosted by Travis Kelce in Nashville on Tuesday.

Ernest Gunar Jr, 27, lured his victim into a car with the promise of a cigarette at a car park in Dover last August, alongside fellow Slovakians Kevin Horvath, 26, and Ivan Turtak, 38.

Brian Parritt (pictured), 94, is one of three veterans who have shared their memories of fighting in the Korean War. He was Mentioned in Dispatches for his exploits.

Kim Kardashian put on a busty display as she was joined by her momager Kris Jenner in a wild campaign for the latest Roberto Cavalli x SKIMS campaign.

The theater of battle between Blake Lively and Justin Baldoni just narrowed with the announcement that he will not be amending the claims in his $400 million defamation lawsuit.

A number of concerns have been raised

An unconventional biopic about legendary actor James Dean has found its leading man in Brandon Flynn.

Right or wrong, we still believe that we live in a world where traditional HPC simulation and modeling at high precision matters more than mashing up the sum total of human knowledge and mixing with the digital exhaust of our lives to create a globe-spanning automation that will leave us all with very little to do and a commensurate amount of wealth and power to show for it. …

Some Thoughts On The Future “Doudna” NERSC-10 Supercomputer was written by Timothy Prickett Morgan at The Next Platform.

Michael Cera been carefully curating his career since he made a name for himself in hits such as 2007's Juno and Super Bad.